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human intestine microsomes (him)  (Corning Life Sciences)

 
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    Corning Life Sciences human intestine microsomes (him)
    Human Intestine Microsomes (Him), supplied by Corning Life Sciences, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/human+intestine+microsomes/pm38142303-37-0-17?v=Corning+Life+Sciences
    Average 90 stars, based on 1 article reviews
    human intestine microsomes (him) - by Bioz Stars, 2026-07
    90/100 stars

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    Enzyme kinetic parameters for CYP and UGT-mediated SPT-07A metabolism in hepatic, renal, and intestinal microsomes of rats, dogs, and humans.

    Journal: Pharmaceutics

    Article Title: Prediction of SPT-07A Pharmacokinetics in Rats, Dogs, and Humans Using a Physiologically-Based Pharmacokinetic Model and In Vitro Data

    doi: 10.3390/pharmaceutics16121596

    Figure Lengend Snippet: Enzyme kinetic parameters for CYP and UGT-mediated SPT-07A metabolism in hepatic, renal, and intestinal microsomes of rats, dogs, and humans.

    Article Snippet: Mixed-gender rat liver microsomes (RLMs), dog liver microsomes (DLMs), human liver microsomes (HLMs), rat intestine microsomes (RIMs), dog intestine microsomes (DIMs), human intestine microsomes (HIMs), and human kidney microsomes (HKMs) were obtained from Xenotech (Kansas City, KS, USA).

    Techniques: In Vivo

    Correlation of UGT2B17 abundance and relative 11β-MNTG levels in HIMs ( A ), HLMs ( B ), and human hepatocytes ( C ).

    Journal: Pharmaceutics

    Article Title: Identification of the Biotransformation Pathways of a Potential Oral Male Contraceptive, 11β-Methyl-19-Nortestosterone (11β-MNT) and Its Prodrugs: An In Vitro Study Highlights the Contribution of Polymorphic Intestinal UGT2B17

    doi: 10.3390/pharmaceutics16081032

    Figure Lengend Snippet: Correlation of UGT2B17 abundance and relative 11β-MNTG levels in HIMs ( A ), HLMs ( B ), and human hepatocytes ( C ).

    Article Snippet: The individual human intestinal microsomes (HIMs) were procured from BioIVT (Westbury, NY, USA), whereas the individual human liver microsomes (HLMs) were in-house generated and available in our laboratory from another study.

    Techniques: